The kinetic profiles of 2-oxo-acid substrates showed some marked differences from that of L-lactatedehydrogenase, suggesting different mechanisms for substrate binding and specificity.
1
There was a good correlation between 51Cr and lactatedehydrogenase release values.
2
KN-62 also antagonized the OA-enhanced release of lactatedehydrogenase from digitonin-permeabilized hepatocytes.
3
To assess cell toxicity, we measured cell viability and lactatedehydrogenase release.
4
Cell death was assessed using in situ end-labeling and lactatedehydrogenase release.
5
They also significantly correlated with serum soluble interleukin-2 receptor and lactatedehydrogenase levels.